Product Details. Generic Flagyl is an antibiotic. It is used to treat bacterial infections of the vagina, skin, bone and joint, respiratory tract and gastrointestinal infections. But it will not work for colds, flu, or other viral infections, also this medication will not treat a vaginal yeast infection.
This medicine is used to treat many kinds of infections, like respiratory, skin, gastrointestinal, and bone and joint infections. It will not work for colds, flu, or other viral infections. Warning: This is a prescription drug and should be used under proper medical guidance and advice. The information provided here is for general educational purposes only and does not constitute medical or pharmaceutical advice which should be sought from qualified medical and pharmaceutical advisers.
Interested in this product? The most serious adverse reactions reported in patients treated with metronidazole have been convulsive seizures, encephalopathy, aseptic meningitis, optic and peripheral neuropathy, the latter characterized mainly by numbness or paresthesia of an extremity.
Since persistent peripheral neuropathy has been reported in some patients receiving prolonged administration of metronidazole, patients should be specifically warned about these reactions and should be told to stop the drug and report immediately to their physicians if any neurologic symptoms occur. In addition, patients have reported headache, syncope, dizziness, vertigo, incoordination, ataxia, confusion, dysarthria, irritability, depression, weakness, and insomnia see WARNINGS.
The most common adverse reactions reported have been referable to the gastrointestinal tract, particularly nausea, sometimes accompanied by headache, anorexia, and occasionally vomiting; diarrhea; epigastric distress; and abdominal cramping and constipation. A sharp, unpleasant metallic taste is not unusual.
Furry tongue, glossitis, and stomatitis have occurred; these may be associated with a sudden overgrowth of Candida which may occur during therapy. Flattening of the T-wave may be seen in electrocardiographic tracings. Urticaria, erythematous rash, Stevens-Johnson Syndrome, toxic epidermal necrolysis, flushing, nasal congestion, dryness of the mouth or vagina or vulva , and fever. Dysuria, cystitis, polyuria, incontinence, and a sense of pelvic pressure.
Instances of darkened urine have been reported by approximately one patient in , Although the pigment which is probably responsible for this phenomenon has not been positively identified, it is almost certainly a metabolite of metronidazole and seems to have no clinical significance.
Proliferation of Candida in the vagina, dyspareunia, decrease of libido, proctitis, and fleeting joint pains sometimes resembling "serum sickness. Patients with Crohn's disease are known to have an increased incidence of gastrointestinal and certain extraintestinal cancers.
There have been some reports in the medical literature of breast and colon cancer in Crohn's disease patients who have been treated with metronidazole at high doses for extended periods of time.
A cause and effect relationship has not been established. Single oral doses of metronidazole, up to 15 g, have been reported in suicide attempts and accidental overdoses. Symptoms reported include nausea, vomiting, and ataxia.
Oral metronidazole has been studied as a radiation sensitizer in the treatment of malignant tumors. Neurotoxic effects, including seizures and peripheral neuropathy, have been reported after 5 to 7 days of doses of 6 to There is no specific antidote for metronidazole overdose; therefore, management of the patient should consist of symptomatic and supportive therapy.
One-day treatment — two grams of FLAGYL, given either as a single dose or in two divided doses of one gram each, given in the same day. Seven-day course of treatment — mg three times daily for seven consecutive days. There is some indication from controlled comparative studies that cure rates as determined by vaginal smears and signs and symptoms, may be higher after a seven-day course of treatment than after a one-day treatment regimen.
The dosage regimen should be individualized. Single-dose treatment can assure compliance, especially if administered under supervision, in those patients who cannot be relied on to continue the seven-day regimen. A seven-day course of treatment may minimize reinfection by protecting the patient long enough for the sexual contacts to obtain appropriate treatment. Further, some patients may tolerate one treatment regimen better than the other.
When repeat courses of the drug are required, it is recommended that an interval of four to six weeks elapse between courses and that the presence of the trichomonad be reconfirmed by appropriate laboratory measures.
Total and differential leukocyte counts should be made before and after re-treatment. For acute intestinal amebiasis acute amebic dysentery : mg orally three times daily for 5 to 10 days. For amebic liver abscess: mg or mg orally three times daily for 5 to 10 days. In the treatment of most serious anaerobic infections, intravenous metronidazole is usually administered initially.
The usual adult oral dosage is 7. A maximum of 4 g should not be exceeded during a hour period. The usual duration of therapy is 7 to 10 days; however, infections of the bone and joint, lower respiratory tract, and endocardium may require longer treatment. Hemodialysis removes significant amounts of metronidazole and its metabolites from systemic circulation. The clearance of metronidazole will depend on the type of dialysis membrane used, the duration of the dialysis session, and other factors.
Distribution Metronidazole is the major component appearing in the plasma, with lesser quantities of metabolites also being present. Renal Impairment Decreased renal function does not alter the single-dose pharmacokinetics of metronidazole. Effect of Dialysis Following a single intravenous infusion or oral dose of metronidazole mg, the clearance of metronidazole was investigated in ESRD subjects undergoing hemodialysis or continuous ambulatory peritoneal dialysis CAPD.
Pediatric Patients In one study, newborn infants appeared to demonstrate diminished capacity to eliminate metronidazole. Microbiology Mechanism of Action Metronidazole, a nitroimidazole, exerts antibacterial effects in an anaerobic environment against most obligate anaerobes.
Raipur, Chhattisgarh. Vadodara No. Estate, Waghodia, Vadodara - , Dist. Vadodara, Gujarat. Rajkot, Gujarat. Have a requirement? Get Best Price. View by: Product Supplier. Location Near Me. Popular Metronidazole Tablet Products. Metrogyl Tablet, Manufacturer: lekar pharma, Prescription. Jackmup International Trading Private Limited. Flagyl Metronidazole Tablet, Mg.
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